Career & application guide

Histotechnologists

Get to know the work, the skills that matter, and how to prepare your next application.

Explore this guide

What do histotechnologists do?

Apply knowledge of health and disease causes to evaluate new laboratory techniques and procedures to examine tissue samples. Process and prepare histological slides from tissue sections for microscopic examination and diagnosis by pathologists. May solve technical or instrument problems or assist with research studies.

This describes a U.S. occupation, not a live vacancy. Individual employers may use different titles and requirements.

Job titles to recognize in your search

O*NET reports these titles for this occupation. Compare the responsibilities in each posting before treating titles as equivalent.

  • Clinical Lab Manager (Clinical Laboratory Manager)
  • Histology Lab Manager (Histology Laboratory Manager)
  • Histology Specialist
  • Histology Technologist
  • Histotechnologist

Core tasks to compare with a job posting

  • Embed tissue specimens into paraffin wax blocks, or infiltrate tissue specimens with wax.
  • Cut sections of body tissues for microscopic examination, using microtomes.
  • Stain tissue specimens with dyes or other chemicals to make cell details visible under microscopes.
  • Compile materials for distribution to pathologists, such as surgical working drafts, requisitions, and slides.
  • Compile and maintain records of preventive maintenance and instrument performance checks according to schedule and regulations.
  • Perform tests by following physician instructions.
  • Operate computerized laboratory equipment to dehydrate, decalcify, or microincinerate tissue samples.
  • Prepare substances, such as reagents and dilution, and stains for histological specimens according to protocols.
  • Resolve problems with laboratory equipment and instruments, such as microscopes, mass spectrometers, microtomes, immunostainers, tissue processors, embedding centers, and water baths.
  • Examine slides under microscopes to ensure tissue preparation meets laboratory requirements.

Prepare an application for this occupation

  1. Check the employer’s requirements, location, schedule and any licenses against your situation.
  2. Choose two or three tasks above that match the posting and your actual experience.
  3. Build a resume evidence worksheet using the skills and software relevant to that employer.
  4. Practice explaining your contribution, decisions and results before an interview.

Ready to plan your search?

Start with histotechnologists as your target. You can change your role in the quiz and tell us your location and work preferences.

Explore related occupations